Zoetis has introduced Lepto Eq Innovator, a vaccine licensed for use in horses 6 months of age or older to aid in the prevention of leptospirosis caused by Leptospira interrogans serovar pomona, known as L. pomona. The vaccine has been shown to be clinically safe for use in foals 3 months of age or older and healthy pregnant mares in the second trimester and has been field tested in more than 1,800 horses. In field safety studies with the administration of 1,808 vaccine doses, 99.8 percent of the horses remained reaction-free. It has also received additional approval for use in broodmares for all three trimesters of pregnancy. Field safety studies that examined the vaccine when used in the first, second and third trimesters of pregnancy showed no systemic or local reactions to vaccination. Prior to launching Lepto Eq Innovator, Zoetis conducted intensive safety and efficacy trials which showed 0 percent urinary shedding in vaccinated horses challenged with L. pomona. Additional studies showed 99.8 percent of vaccinated horses were reaction-free with no adverse events.