Zentrol Chewable Tablets are for dogs exhibiting stress-related behaviors. The tablets are composed of natural ingredients, Souroubea spp, containing betulinic acid, and Platanus spp. In vivo and in vitro studies have shown interaction with the GABA-BZD receptor and have been shown to reduce stress-related behaviors, including those caused by noise phobias. Clinically proven to begin working in 60 minutes. A preliminary 29-day toxicology study and a 28-day safety trial demonstrated no untoward effects on the health of dogs when administered up to 10 times the intended dose. Available in a 3.5 gram scored, beef flavored, easy-to-give tablet.